of space-faring tends toward terraforming to preclude extinction by random celestial events wiping out our home planet.
Then, maybe, thousands, even millions of years from now, a much more technologically advanced multi-planetary "civilization" (not sure classified as even "human" anymore) would have some space-warping/wormhole gadgetry to tool around the larger portion of our galactic arm.
Even then, of course, most of the Universe would remain forever physically unexplorable, let alone our tiny corner of it.
One can imagine, of course, the possibility that already existing super-advanced beings out there somewhere have mastered the technology of being "in their own headspace" anywhere in the Universe they want to be.
As an addendum, I talk to some of these beings sometimes, late at night, when all is quiet. And they tell me that, if we all work together, peacefully, with kindness, understanding, and deep respect for each other, and our planetary species-partners, everything is gonna be alright.
And I'm not even high!