Reversing Aging: Reprogramming to recover youthful epigenetic information and restore vision

[NNadir]

9. It may not be exactly the same type of approach but yes, there's a lot of gene therapy work on...

...diabetes. Here's a relatively recent review of what's being done:

Type 1 and 2 diabetes mellitus: A review on current treatment approach and gene therapy as potential intervention (Tan et al., Diabetes & Metabolic Syndrome: Clinical Research & Reviews Volume 13, Issue 1, January–February 2019, Pages 364-372)

It is well understood that diabetes has a genetic component.

We are in the early stages of gene therapy. A "one shot" genetic therapy has been approved for curing a certain rare form of blindness.

The economics of one shot medications depends on the prevalence of the disease. As diabetes is common throughout the world, assuming that a "one size fits all" gene modification works, and no designer genetic manipulation is necessary, it might actually fall into the category of "expensive but often affordable."

I have not personally studied gene therapy approaches to diabetes, but it seems that a great deal has been written about it.