Effect of Higher-Dose Ivermectin for 6 Days vs Placebo

[Yonnie3]

Effect of Higher-Dose Ivermectin for 6 Days vs Placebo on Time to Sustained Recovery in Outpatients With COVID-19A Randomized Clinical Trial

Susanna Naggie, MD, MHS1,2; David R. Boulware, MD, MPH3; Christopher J. Lindsell, PhD4; et al

JAMA. Published online February 20, 2023. doi:10.1001/jama.2023.1650

Key Points

Question Does ivermectin, with a maximum targeted dose of 600 μg/kg daily for 6 days, compared with placebo, shorten symptom duration among adult (≥30 years) outpatients with symptomatic mild to moderate COVID-19?

Findings In this double-blind, randomized, placebo-controlled platform trial including 1206 US adults with COVID-19 during February 2022 to July 2022, the median time to sustained recovery was 11 days in the ivermectin group and 11 days in the placebo group. In this largely vaccinated (84%) population, the posterior probability that ivermectin reduced symptom duration by more than 1 day was less than 0.1%.

Meaning These findings do not support the use of ivermectin among outpatients with COVID-19.

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https://jamanetwork.com/journals/jama/fullarticle/2801827

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I'm not surprised there is no benefit because of who advocates for its use.

[House of Roberts]

1. It might make you feel better if you also had worms,

along with the Covid. Maybe the Ivermectin fans nearly always have worms too?

[Yonnie3]

3. "The nematodes are there and here, In each part of the lithosphere!"

Last edited Mon Feb 20, 2023, 02:14 PM - Edit history (1)

https://www.npr.org/sections/goatsandsoda/2018/02/17/586214508/a-dr-seuss-like-poem-about-the-woman-who-pulled-14-worms-from-her-eye

You Don't Want To Know What Was In Abby Beckley's Eye

A cattle ranch is down this road!
And on the ranch? A nematode!

Where once before just tears had flowed
Her eye now held a different load!
A nematode? A nematode!
And what, pray tell's, a nematode?

"But heavens abound! Is that a worm?!"
Gasped Abby as she watched it squirm
betwixt her fingers and across the sink.
She didn't, daren't, dursen't blink!

The nematodes are there and here,
In each part of the lithosphere!
They live in you, they live in us,
It seems like they're ubiquitous!

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[Frances]

2. If you are a rat with worms

You should definitely take ivermectin
If you are a rat who listens to Trump, take ivermectin.
If you are a normal person, listen to a true health professional

[LetMyPeopleVote]

4. Who is surprised by this?

Link to tweet

[SpamWyzer]

5. In a past life

as an organic coffee grower in Central America, I was infected by botflies and other parasites due to prolonged periods in the coffee courts. The local doctors always treated this problem in farmers and agriculture workers with a shot in the butt with Ivermectin. I now understand it is something to be limited since it damages the kidneys after even short treatment. As for Covid; only stupidity would prescribe it.